In a small 2019 study of 36 people who took collagen, participants reported no side effects. They may recommend temporarily stopping the supplement until the test is complete.Ĭollagen naturally exists in the body, so at typical doses, it is unlikely to cause serious side effects. b-HCG, which is a hormone present in the blood during pregnancyĪ person should tell a doctor about all supplements before having any tests. However, taking biotin at high doses may interfere with some lab tests, including tests for: There is no evidence biotin is toxic at high doses. In contrast, no randomized studies have proven that biotin can improve skin conditions.Īt typical dosages, biotin and collagen are likely safe. The analysis reported no adverse events and suggests that collagen could be a useful supplement for reducing the signs of aging. Two of the studies found improvements in skin hydration and elasticity with collagen tripeptide, and one found that collagen dipeptide improved the appearance of skin aging proportionate to the quantity of collagen dipeptide a person took. In eight studies of collagen hydrolysate, researchers found evidence that collagen might improve skin aging, cellulite, skin dryness, and ulcers. The review included 11 studies with 805 participants. Otherwise, collagen can be a better option as there is more evidence to suggest it helps improve the skin’s appearance.Ī 2019 systematic review of prior studies on oral collagen supplements supports the idea that collagen may improve skin health. If a person has a biotin deficiency, taking biotin may improve the health of their skin. This is a significant limitation that can bias research. However, a collagen nutraceutical manufacturer funded the study. The collagen group had significant improvements in all four measures, and these improvements persisted for 4 weeks of follow-up after the initial 12-week period. Researchers then used validated measures of hydration, elasticity, roughness, and density to assess skin health and appearance. Participants used the supplement or placebo for 12 weeks. All participants were over the age of 35. However, supplementing with biotin is unlikely to be harmful if a person takes a supplement at typical levels.Ī 2019 randomized placebo-controlled study assessed the effects of a collagen product on skin health in 36 women. No recent strong evidence suggests that biotin can make the hair significantly thicker or dramatically reverse hair loss in people who do not have a biotin deficiency. The authors of the study suggest that biotin may improve hair loss in people with and without biotin deficiency, but their study only offers weak evidence for this claim due to its low number of participants. Of this group, 11 people (38%) reported significant declines in hair loss. Of these, five people (23%) reported a significant decline in hair loss.Īn additional 29 people without biotin deficiency chose to take 1,000 mcg of biotin per day. 22 people had biotin deficiency and took 1,000 micrograms (mcg) of biotin per day for 3 months. For example, in a small 2021 study of 156 females who had weight loss surgery, 72% reported hair loss. Supplementing with biotin may reduce hair loss in people with this condition.īiotin may also work to help regrow hair. One of the key signs of biotin deficiency is hair loss.
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